The 1st International Conference on Pharmaceutical Sciences and Pharmacy

Fernandez, Stefany S. A. (2020) The 1st International Conference on Pharmaceutical Sciences and Pharmacy. In: UNSPECIFIED.

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Abstract

Fatigue is a condition of weakness or reduced ability to do a job. When there is a lack of energy, people have their way of dealing with it. One of the plants of the Family Sterculiaceae empirically used by the people of East Nusa Tenggara as a stamina enhancer in heavy workers, pre and postpartum mothers to increase energy during and after birth is Faloak (Sterculia quadrifida R.Br.). the results of acute toxicity tests on test animals indicate that Faloak infusion is safe. Phytochemical screening results show the content of flavonoids, anthraquinone, saponins, cardenolides, and tannins. The method used in this test is a Weight-loaded Forced Swimming Test (WFST), the mice are forced to swim with a load of ± 10% of body weight before and after the preparation of Faloak infusion with a concentration of 50%, 75%, and 100% for 8 days. Length of swimming time and body weight were tested using the One Way ANOVA Test and Paired T-Test, the data showed no effect of mice weight gain on swimming time (p <0.05). The results showed the anti-fatigue effect of faloak infusion concentrations of 50%, 75%, and 100% and significantly different from the control group. From these results, it can be considered that infusion of faloak stem bark concentrations of 50%, 75% and 100% have anti-fatigue effects. Keywords: Anti fatique, Faloak, Sterculia quadrifida R.Br., WFST, mice

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